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PEOPLE'S PHARMACY Drug warnings too often ignored

...A lower dose might be less likely to cause problems, but if that doesn't help, ask your doctor about alternative approaches.

Caverject (alprostadil) injected into the penis is less likely to cause headaches.

Q: My wife and I both have cholesterol issues.

I take Lipitor, and she's on Crestor.

In the winter, we always have grapefruit for breakfast.

I work out nearly every day.

Soon after starting Lipitor, my arm muscles became sore.

I continued to work out and didn't think much of it.

I just lightened the weights that I use for the bicep exercises.

A few weeks later, the muscles around my knee began to ache.

Now my lower back also hurts.

The doctor said that muscle pain from Lipitor is rare, but I wonder whether the grapefruit is part of the problem.

If so, why hasn't my wife had trouble?

A: Your symptoms might be related to a higher dose of Lipitor brought on by an interaction with grapefruit.

Crestor is not affected.

Grapefruit can raise blood levels of dozens of different medicines and increase the possibility of side effects.

The grapefruit effect can last up to 48 hours, so eating grapefruit in the morning and taking medicine at night doesn't solve the problem.

For more details, we are sending you our Guides to Grapefruit Interactions and Cholesterol-Lowering Drugs.

Anyone who would like copies, please send $2 in check or money order with a long, (No.

10), stamped (63 cents), self-addressed envelope to: Graedons' People's Pharmacy, No.

JL-97, ...

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