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Multimedia News Release - Heart Failure Society Supports the Use ...... Residua have been detected many years after discontinuation of hydralazine. Symptomatic hypotension may occur with even small doses of BiDil. BiDil should be used with caution in volume depleted or hypotensive patients. Hydralazine can cause tachycardia potentially leading to myocardial ischemia and anginal attacks. Careful clinical monitoring is recommended when BiDil is administered to patients with acute myocardial infarction to avoid hypotension and tachycardia. Isosorbide dinitrate therapy may aggravate angina associated with hypertrophic cardiomyopathy. Hydralazine has been associated with peripheral neuritis, evidenced by paresthesia, numbness and tingling, which may be related to an antipyridoxine effect. Caution should be exercised if BiDil is
used with MAO inhibitors, alcohol, sildenafil, vardenafil or tadalafil.Headache (50%) and dizziness (32%) were the two most frequent adverse
events in A-HeFT and were more than twice as frequent in the BiDil group.Viagra is a registered trademark and Revatio is a trademark of Pfizer,
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